Lactoferrin

An iron-binding protein that was originally characterized as a milk protein. It is widely distributed in secretory fluids and is found in the neutrophilic granules of LEUKOCYTES. The N-terminal part of lactoferrin possesses a serine protease which functions to inactivate the TYPE III SECRETION SYSTEM used by bacteria to export virulence proteins for host cell invasion.

Also Known As:

Lactotransferrin

Pharmalogical Action Categories:

Anti-Infective Agents

Enzymes and Coenzymes: 1
- Enzymes: 155591
  - Hydrolases: 2206
    - Peptide Hydrolases: 24289
      - Serine Proteases: 3808
        Serine Endopeptidases: 11
        Lactoferrin: 2698
      - Endopeptidases: 643
        Serine Endopeptidases: 11
        Lactoferrin: 2698
Carbohydrates: 22516
- Glycoconjugates: 1370
  - Glycoproteins: 25180
    - Lactoferrin: 2698
Amino Acids, Peptides, and Proteins: 1
- Proteins: 496323
  - Glycoproteins: 25180
    - Lactoferrin: 2698
  - Carrier Proteins: 13306
    - Iron-Binding Proteins: 176
      - Transferrins: 33
        Lactoferrin: 2698
  - Globulins: 3119
    - Lactoglobulins: 379
      - Lactoferrin: 2698
  - Dietary Proteins: 2433
    - Dietary Animal Proteins: 18
      - Milk Proteins: 873
        Whey Proteins: 725
        Lactoglobulins: 379
        Lactoferrin: 2698
  - Metalloproteins: 169
    - Iron-Binding Proteins: 176
      - Transferrins: 33
        Lactoferrin: 2698

Angela Pasinato Selected Research

Angela Pasinato Research Topics

Disease

Drug/Important Bio-Agent (IBA)

Therapy/Procedure